- The Seleucid Dynasty was founded in 312 B.C. by one of Alexander the Great's generals, Seleucid I Nicator, after the empire
was split between the Diodochi. The Seleucid Dynasty ruled over much of Alexander's eastern domain, from Anatolia to (at it's
greatest extent) Bactria. The dynasty finally collapsed to the rising Roman hegemony in the East in 63 B.C.